基因名称(Gene Name)
NCAPH2 CAPH2
免疫原
Synthesized peptide derived from human CNDH2 AA range: 501-551
特异性
This antibody detects endogenous levels of CNDH2 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010],
功能
function:Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CND2 H2 (condensin-2 subunit 2) family.,subcellular location:Distributed along the arms of chromosomes assembled in vivo and in vitro.,subunit:Component of the condensin-2 complex, which contains the smc2 and smc4 heterodimer, and three non SMC subunits, ncapg2, ncaph2 and ncapd3 that probably regulate the complex.,
