免疫原
Synthesized peptide derived from human HCFC2 AA range: 347-397
特异性
This antibody detects endogenous levels of HCFC2 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008],
功能
similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 4 Kelch repeats.,subunit:Binds MLL. Component of the MLL complex, at least composed of MLL, ASH2L, RBBP5, DPY30, WDR5, MEN1, HCFC1 and HCFC2.,tissue specificity:Highly expressed in testis. Detected at lower levels in spleen, thymus, prostate, ovary, small intestine and colon.,
