基因名称(Gene Name)
SLC23A1 SVCT1 YSPL3
免疫原
Synthesized peptide derived from human S23A1 AA range: 237-287
特异性
This antibody detects endogenous levels of S23A1 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
功能
alternative products:Experimental confirmation may be lacking for some isoforms,function:Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.,miscellaneous:Treatment with the protein kinase C stimulator PMA results in a 10-fold decrease in ascorbate accumulation in transfected cells.,PTM:Phosphorylated.,similarity:Belongs to the xanthine/uracil permease family. SLC23A subfamily.,tissue specificity:Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.,
