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货号: YP-mAb-10904
促销价:

产品介绍

反应种属
Human; Mouse; Rat
应用范围
WB
抗体类型
单克隆抗体
基因名称(Gene Name)
LSM2 C6orf28 G7B
蛋白名称
LSM2
分子量(DA)
免疫原
Synthesized peptide derived from human LSM2 AA range: 33-83
特异性
This antibody detects endogenous levels of human LSM2
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源
Monoclonal, Mouse,IgG
稀释比例
Western Blot: 1/500 - 1/2000
纯化工艺
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度
1 mg/ml
储存
-20°C/1 year
其他名称
U6 snRNA-associated Sm-like protein LSm2 (Protein G7b;Small nuclear ribonuclear protein D homolog;snRNP core Sm-like protein Sm-x5)
背景
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011],
功能
function:Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the snRNP Sm proteins family.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, MABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8. LSm subunits form a heteromer with a donut shape.,

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