基因名称(Gene Name)
UGT8 CGT UGT4
免疫原
Synthesized peptide derived from human CGT
特异性
This antibody detects endogenous levels of human CGT
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.45;Ceramide UDP-galactosyltransferase;Cerebroside synthase;UDP-galactose-ceramide galactosyltransferase)
背景
UDP glycosyltransferase 8(UGT8) Homo sapiens The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011],
功能
catalytic activity:UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine.,function:Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.,online information:2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor,pathway:Sphingolipid metabolism; galactosylceramide biosynthesis.,similarity:Belongs to the UDP-glycosyltransferase family.,
