基因名称(Gene Name)
GRIN2D GluN2D NMDAR2D
蛋白名称
Glutamate [NMDA] receptor subunit epsilon-4 (EB11) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D)
免疫原
Synthesized peptide derived from human GRIN2D Monoclonal
特异性
This antibody detects endogenous levels of GRIN2D.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
Glutamate [NMDA] receptor subunit epsilon-4 (EB11) (N-methyl D-aspartate receptor subtype 2D) (NMDAR2D) (NR2D)
背景
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010],
功能
function:NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.,similarity:Belongs to the glutamate-gated ion channel (TC 1.A.10) family.,subunit:Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B).,
