免疫原
Synthesized peptide derived from NOP56 at AA range: 191-240
特异性
NOP56 Monoclonal Antibody detects endogenous levels of NOP56
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
其他名称
Nucleolar protein 56 (Nucleolar protein 5A)
背景
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016],
功能
function:Required for 60S ribosomal subunit biogenesis.,similarity:Belongs to the NOP5/NOP56 family.,similarity:Contains 1 Nop domain.,subunit:Interacts with NOP1 and NOP58.,
