背景
WD40 repeat proteins are key components of many essential biologic functions. They
regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for
simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of
WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a
conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004
