蛋白名称
U8 snoRNA-decapping enzyme (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 16) (Nudix motif 16) (U8 snoRNA-binding protein H29K) (m7GpppN-mRNA hydrolase)
免疫原
Synthesized peptide derived from human NUD16 AA range: 2-52
特异性
This antibody detects endogenous levels of human NUD16
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
功能
function:Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.,induction:By T-cell growth factor and interleukin-2.,PTM:A 9 kDa form is produced by proteolytic processing of a 15 kDa protein.,similarity:Contains 1 saposin B-type domain.,subcellular location:Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.,tissue specificity:Expressed in natural killer and T-cells.,
