基因名称(Gene Name)
MKRN3 D15S9 RNF63 ZNF127
蛋白名称
Probable E3 ubiquitin-protein ligase makorin-3 (EC 6.3.2.-) (RING finger protein 63) (Zinc finger protein 127)
免疫原
Synthesized peptide derived from human MKRN3 AA range: 237-287
特异性
This antibody detects endogenous levels of human MKRN3
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008],
功能
function:Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1.,similarity:Belongs to the peptidase U48 family.,tissue specificity:Ubiquitous.,
