基因名称(Gene Name)
RAG1 RNF74
蛋白名称
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 6.3.2.-)]
免疫原
Synthesized peptide derived from human RAG1 AA range: 894-944
特异性
This antibody detects endogenous levels of human RAG1
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.,similarity:Contains 1 follistatin-like domain.,similarity:Contains 10 EGF-like domains.,subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.,subunit:Interacts with AP1G1. Interacts with NOTCH1.,tissue specificity:Expressed in brain, spinal cord and adrenal gland.,
功能
function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.,similarity:Contains 1 follistatin-like domain.,similarity:Contains 10 EGF-like domains.,subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.,subunit:Interacts with AP1G1. Interacts with NOTCH1.,tissue specificity:Expressed in brain, spinal cord and adrenal gland.,
