基因名称(Gene Name)
MEX3A RKHD4
蛋白名称
RNA-binding protein MEX3A (RING finger and KH domain-containing protein 4)
免疫原
Synthesized peptide derived from human MEX3A AA range: 48-98
特异性
This antibody detects endogenous levels of human MEX3A
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
function:May act as an inhibitor of TGF-beta signaling.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,subunit:Interacts with TGFB1, TGFB2 and TGFB3.,tissue specificity:Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.,
功能
function:May act as an inhibitor of TGF-beta signaling.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,subunit:Interacts with TGFB1, TGFB2 and TGFB3.,tissue specificity:Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.,