基因名称(Gene Name)
CBLC CBL3 RNF57
蛋白名称
Signal transduction protein CBL-C (RING finger protein 57) (SH3-binding protein CBL-3) (SH3-binding protein CBL-C)
免疫原
Synthesized peptide derived from human CBLC AA range: 219-269
特异性
This antibody detects endogenous levels of human CBLC
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
Thymopoietin encoded by TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
功能
regulation of transcription,