基因名称(Gene Name)
NABP2 OBFC2B SSB1 LP3587
蛋白名称
SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit
免疫原
Synthesized peptide derived from human SOSB1 AA range: 70-120
特异性
This antibody detects endogenous levels of human SOSB1
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008],
功能
function:Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.,PTM:Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.,similarity:Contains 1 DSL domain.,similarity:Contains 8 EGF-like domains.,subunit:Interacts with Notch receptors.,tissue specificity:Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.,
