基因名称(Gene Name)
CCDC34 RAMA3 L15
蛋白名称
Coiled-coil domain-containing protein 34 (Renal carcinoma antigen NY-REN-41)
免疫原
Synthesized peptide derived from human CCD34 AA range: 249-299
特异性
This antibody detects endogenous levels of human CCD34
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015],
功能
function:May be involved in controlling the timing of organ formation during development.,induction:Down-regulated by retinoic acid in Tera-2 cells.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 filamin repeat.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 2 B box-type zinc fingers.,similarity:Contains 6 NHL repeats.,tissue specificity:Specifically expressed in testis.,