基因名称(Gene Name)
LHX6 LHX6.1
蛋白名称
LIM/homeobox protein Lhx6 (LIM homeobox protein 6) (LIM/homeobox protein Lhx6.1)
免疫原
Synthesized peptide derived from human LHX6 AA range: 257-307
特异性
This antibody detects endogenous levels of human LHX6
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012],
功能
function:Binds predominantly GDP, and also GTP.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Down-regulated in cutaneous melanoma cells but not in breast cancer cells.,
