基因名称(Gene Name)
SRPRB PSEC0230
蛋白名称
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
免疫原
Synthesized peptide derived from human SRPRB AA range: 174-224
特异性
This antibody detects endogenous levels of human SRPRB
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010],
功能
similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,