基因名称(Gene Name)
ASRGL1 ALP CRASH
免疫原
Synthesized peptide derived from human ASGL1 AA range: 57-107
特异性
This antibody detects endogenous levels of ASGL1 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010],
功能
catalytic activity:L-asparagine + H(2)O = L-aspartate + NH(3).,function:Acts in asparagine catabolism. May be involved in astroglial production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions.,induction:By 5-alpha-di-hydrotestosterone and progesterone.,similarity:Belongs to the Ntn-hydrolase family.,subcellular location:Midpiece of sperm tail.,tissue specificity:Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over-expressed in uterine, mammary, prostatic and ovarian carcinoma.,
