免疫原
Synthesized peptide derived from human GAG2E AA range: 62-112
特异性
This antibody detects endogenous levels of GAG2E at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],
功能
function:Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes.,function:Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes. Completely silent in normal adult tissues, except testis.,similarity:Belongs to the GAGE family.,tissue specificity:Expressed in a variety of tumor tissues but not in normal tissues, except testis.,tissue specificity:Expressed in some prostate cancer tissues but not in normal prostate tissue.,tissue specificity:Not expressed in normal tissues, except in testis, but expressed by a large proportion of tumors of various histological origins.,
