基因名称(Gene Name)
CDY2A CDY2; CDY2B
免疫原
Synthesized peptide derived from human CDY2 AA range: 434-484
特异性
This antibody detects endogenous levels of CDY2 at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:May have histone acetyltransferase activity.,similarity:Contains 1 chromo domain.,tissue specificity:Testis specific.,
