免疫原
Synthesized peptide derived from human PARG AA range: 140-190
特异性
This antibody detects endogenous levels of PARG at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],
功能
function:Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,subunit:Monomer.,tissue specificity:Expressed at high levels in liver and kidney and lower levels in heart, intestine and skeletal muscle.,
