基因名称(Gene Name)
ZYG11B KIAA1730
免疫原
Synthesized peptide derived from human ZY11B AA range: 432-482
特异性
This antibody detects endogenous levels of ZY11B at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
Mix paired-like homeobox(MIXL1) Homo sapiens Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]).[supplied by OMIM, Mar 2008],
功能
function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 2 ARM repeats.,similarity:Contains 3 LRR (leucine-rich) repeats.,subunit:Interacts with TCEB1/Elongin C. Part of an E3 ubiquitin ligase complex including ZYG11B, CUL2 and Elongin BC.,