免疫原
Synthesized peptide derived from human HP1B3 AA range: 283-333
特异性
This antibody detects endogenous levels of HP1B3 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a member of the testis-specific protein Y-encoded, TSPY-like/SET/nucleosome assembly protein-1 superfamily. The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression. This protein may play a role in the suppression of tumor growth. [provided by RefSeq, Sep 2009],
功能
function:Component of heterochromatin, may be involved in chromatin structure and function.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the histone H1/H5 family.,similarity:In the C-terminal section; belongs to the histone H1/H5 family.,subunit:Interacts with CBX5.,
