基因名称(Gene Name)
ZNF260 ZFP260
免疫原
Synthesized peptide derived from human ZN260 AA range: 64-114
特异性
This antibody detects endogenous levels of ZN260 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
function:May be involved in transcriptional regulation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 8 C2H2-type zinc fingers.,
功能
caution:It is uncertain whether Met-1 or Met-4 is the initiator.,function:Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator.,induction:Up-regulated by activation of alpha1-adrenergic receptors.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 13 C2H2-type zinc fingers.,subunit:Binds DNA. Interacts with GATA4.,
