基因名称(Gene Name)
SNTN S100A1L
免疫原
Synthesized peptide derived from human SNTAN AA range: 65-115
特异性
This antibody detects endogenous levels of SNTAN at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
功能
function:May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules.,miscellaneous:'Sentan' means 'tip' in Japanese.,similarity:Belongs to the S-100 family.,subcellular location:Expressed exclusively at the cilium tip where it localizes between the cell membrane and peripheral A-subfibers.,
