基因名称(Gene Name)
MTPAP PAPD1
免疫原
Synthesized peptide derived from human PAPD1 AA range: 445-495
特异性
This antibody detects endogenous levels of PAPD1 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011],
功能
catalytic activity:ATP + RNA(n) = diphosphate + RNA(n+1).,function:Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA.,similarity:Belongs to the DNA polymerase type-B-like family.,tissue specificity:Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle.,
