基因名称(Gene Name)
UNC5CL ZUD
免疫原
Synthesized peptide derived from human UN5CL AA range: 80-130
特异性
This antibody detects endogenous levels of UN5CL at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013],
功能
function:Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets.,similarity:Belongs to the unc-5 family.,similarity:Contains 1 death domain.,similarity:Contains 1 ZU5 domain.,subunit:Interacts with p65/RELA and NFKB1.,tissue specificity:Expressed in pancreas, liver and kidney.,