基因名称(Gene Name)
APIP CGI-29
免疫原
Synthesized peptide derived from human MTNB AA range: 133-183
特异性
This antibody detects endogenous levels of MTNB at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).[supplied by OMIM, Dec 2008],
功能
cofactor:Binds 1 zinc ion per subunit .,function:Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death.,similarity:Belongs to the aldolase class II family. APIP subfamily.,subunit:Interacts with APAF1.,tissue specificity:Ubiquitously expressed with high expression in skeletal muscle, heart and kidney.,
