基因名称(Gene Name)
NIF3L1 ALS2CR1 MDS015 My018
免疫原
Synthesized peptide derived from human NIF3L AA range: 85-135
特异性
This antibody detects endogenous levels of NIF3L at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kapMAB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kapMAB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008],
功能
similarity:Belongs to the UPF0135 (NIF3) family.,subunit:Homodimer. Interacts with COPS2 (By similarity). Interacts with THOC7.,