基因名称(Gene Name)
RPRD1B C20orf77 CREPT
免疫原
Synthesized peptide derived from human RPR1B AA range: 248-298
特异性
This antibody detects endogenous levels of RPR1B at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kapMAB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011],
功能
sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the UPF0400 (RTT103) family.,similarity:Contains 1 CID domain.,
