基因名称(Gene Name)
SRPX ETX1
免疫原
Synthesized peptide derived from human SRPX AA range: 234-284
特异性
This antibody detects endogenous levels of SRPX at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
function:May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 SAP domain.,tissue specificity:Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors.,
功能
alternative products:Additional isoforms seem to exist,function:May be involved in phagocytosis during disk shedding, cell adhesion to cells other than the pigment epithelium or signal transduction.,similarity:Contains 1 HYR domain.,similarity:Contains 3 Sushi (CCP/SCR) domains.,subcellular location:Possibly surface of photoreceptor cell.,tissue specificity:Retina and heart; less in placenta, pancreas, lung, liver, skeletal muscle, kidney and brain.,
