基因名称(Gene Name)
PNMT PENT
免疫原
Synthesized peptide derived from human PNMT AA range: 96-146
特异性
This antibody detects endogenous levels of PNMT at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012],
功能
catalytic activity:S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.,function:Converts noradrenaline to adrenaline.,pathway:Catecholamine biosynthesis; epinephrine biosynthesis; epinephrine from norepinephrine: step 1/1.,similarity:Belongs to the NNMT/PNMT/TEMT family.,
