基因名称(Gene Name)
KIAA0284 FAM68C
免疫原
Synthesized peptide derived from human K0284 AA range: 454-504
特异性
This antibody detects endogenous levels of K0284 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor caMABle of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008],
功能
function:Plays a role in microtubule organization.,similarity:Belongs to the CEP170 family.,similarity:Contains 1 FHA domain.,
