免疫原
Synthesized peptide derived from human 2B1E AA range: 194-244
特异性
This antibody detects endogenous levels of 2B1E at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008],
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the tigger transposable element derived protein family.,similarity:Contains 1 DDE domain.,similarity:Contains 1 HTH CENPB-type DNA-binding domain.,similarity:Contains 1 HTH psq-type DNA-binding domain.,
