基因名称(Gene Name)
TBC1D12 KIAA0608
免疫原
Synthesized peptide derived from human TBC12 AA range: 596-646
特异性
This antibody detects endogenous levels of TBC12 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
titin-cap(TCAP) Homo sapiens Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq, Jul 2008],
功能
function:May act as a GTPase-activating protein for Rab family protein(s).,similarity:Contains 1 Rab-GAP TBC domain.,
