基因名称(Gene Name)
DGAT1 AGRP1 DGAT
免疫原
Synthesized peptide derived from human DGAT1 AA range: 405-455
特异性
This antibody detects endogenous levels of DGAT1 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes an multipass transmembrane protein that functions as a key metabolic enzyme. The encoded protein catalyzes the conversion of diacylglycerol and fatty acyl CoA to triacylglycerol. This enzyme can also transfer acyl CoA to retinol. Activity of this protein may be associated with obesity and other metabolic diseases. [provided by RefSeq, Jul 2013],
功能
catalytic activity:Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.,function:Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly.,pathway:Lipid metabolism; glycerolipid metabolism.,similarity:Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.,
