免疫原
Synthesized peptide derived from human 2B1B AA range: 214-264
特异性
This antibody detects endogenous levels of 2B1B at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins which have been classified into several families of related genes. The protein encoded by this gene is a member of the subgroup of transporter with unidentified substrates within the Na+ and Cl- coupled transporter family. This gene is expressed in kidney, and its alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008],
功能
function:Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subcellular location:Located in the apical brush border membrane of kidney proximal tubule cells.,tissue specificity:Kidney and small intestine.,
