基因名称(Gene Name)
AKIRIN2 C6orf166
免疫原
Synthesized peptide derived from human AKIR2 AA range: 14-64
特异性
This antibody detects endogenous levels of AKIR2 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
功能
function:Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.,miscellaneous:'Akiraka ni suru' means 'making things clear' in Japanese. The name is given based on the presence of the clear nuclear localization signal.,similarity:Belongs to the akirin family.,subunit:Interacts with YWHAB.,tissue specificity:Widely expressed with the highest expression in peripheral blood leukocytes.,
