基因名称(Gene Name)
LCE1F LEP6
免疫原
Synthesized peptide derived from human LCE1F AA range: 22-72
特异性
This antibody detects endogenous levels of LCE1F at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
功能
function:Precursors of the cornified envelope of the stratum corneum.,induction:By UVB.,miscellaneous:Belongs to the LCE cluster present on 1q21.,similarity:Belongs to the LCE family.,tissue specificity:Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta. Expression is observed in the fibroblasts.,