基因名称(Gene Name)
MAN2B2 KIAA0935
免疫原
Synthesized peptide derived from human MA2B2 AA range: 906-956
特异性
This antibody detects endogenous levels of MA2B2 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the glycosyl hydrolase 38 family.,