免疫原
Synthesized peptide derived from human EF1DL AA range: 16-66
特异性
This antibody detects endogenous levels of EF1DL at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014],
功能
function:Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Binds GRB7 and PLXNB1. Interacts with UBXD5.,tissue specificity:Mostly expressed in brain and liver.,
