基因名称(Gene Name)
ZNF350 ZBRK1
免疫原
Synthesized peptide derived from human ZN350 AA range: 346-396
特异性
This antibody detects endogenous levels of ZN350 at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
功能
function:Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 8 C2H2-type zinc fingers.,subcellular location:Associated with the nuclear matrix.,subunit:Interacts with BRCA1.,tissue specificity:Widely expressed.,
