基因名称(Gene Name)
SIX6OS1 C14orf39
免疫原
Synthesized peptide derived from human S6OS1 AA range: 511-561
特异性
This antibody detects endogenous levels of S6OS1 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
RAS guanyl releasing protein 3(RASGRP3) Homo sapiens Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008],
功能
function:May be involved in eye development through regulation of the SIX6 transcription factor.,tissue specificity:Highest expression in retina, skeletal muscle and colon.,
