基因名称(Gene Name)
FSTL5 KIAA1263
免疫原
Synthesized peptide derived from human FSTL5 AA range: 315-365
特异性
This antibody detects endogenous levels of FSTL5 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011],
功能
similarity:Contains 1 Kazal-like domain.,similarity:Contains 2 EF-hand domains.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,
