基因名称(Gene Name)
PPA1 IOPPP PP
免疫原
Synthesized peptide derived from human IPYR AA range: 162-212
特异性
This antibody detects endogenous levels of IPYR at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Diphosphate + H(2)O = 2 phosphate.,cofactor:Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product.,similarity:Belongs to the PPase family.,subunit:Homodimer.,tissue specificity:Expressed ubiquitously.,
