免疫原
Synthesized peptide derived from human CP072 AA range: 55-105
特异性
This antibody detects endogenous levels of CP072 at Human/Mouse
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
Poly(A)-binding proteins (MABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. MABPC4 or IMABP (inducible MABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased MABPC4 mRNA levels in T cells approximately 5-fold. MABPC4 contains 4 RNA-binding domains and proline-rich C terminus. MABPC4 is localized primarily to the cytoplasm. It is suggested that MABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. MABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated Mouse platelets. MABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript va
功能
similarity:Belongs to the UPF0472 family.,
