基因名称(Gene Name)
LINC00242 C6orf122 NCRNA00242
免疫原
Synthesized peptide derived from human CF122 AA range: 125-175
特异性
This antibody detects endogenous levels of CF122 at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009],
功能
cofactor:Binds 2 calcium ions per subunit.,function:Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.,similarity:Contains 1 pentaxin domain.,tissue specificity:Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis.,
