基因名称(Gene Name)
BIRC8 ILP2
免疫原
Synthesized peptide derived from human BIRC8 AA range: 122-172
特异性
This antibody detects endogenous levels of BIRC8 at Human
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008],
功能
function:Protects against apoptosis mediated by BAX.,similarity:Belongs to the IAP family.,similarity:Contains 1 BIR repeat.,similarity:Contains 1 RING-type zinc finger.,subunit:Binds to caspase-9.,tissue specificity:Testis specific in normal tissues.,
