基因名称(Gene Name)
TMEM66 SARAF XTP3 HSPC035 NPD003 PSEC0019 UNQ1967/PRO4499
免疫原
Synthesized peptide derived from human SARAF AA range: 277-327
特异性
This antibody detects endogenous levels of SARAF at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景
This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],
功能
similarity:Belongs to the TMEM66 family.,tissue specificity:Highly expressed in macrophages.,
