基因名称(Gene Name)
DCBLD2 CLCP1 ESDN
免疫原
Synthesized peptide derived from human DCBD2 AA range: 142-192
特异性
This antibody detects endogenous levels of DCBD2 at Human/Mouse/Rat
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.359% sodium azide.
纯化工艺
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Discoidin, CUB and LCCL domain-containing protein 2 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1) (Endothelial and smooth muscle cell-derived neuropilin-like protein)
背景
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008],
功能
induction:Increased in lung cancers during the process of tumor progression.,similarity:Contains 1 CUB domain.,similarity:Contains 1 F5/8 type C domain.,similarity:Contains 1 LCCL domain.,tissue specificity:Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells.,
